Treatment options for infections caused by multidrug-resistant Gram-negative bacteria: a guide to good clinical practice - Supplementary Tables

The rapid emergence of multidrug-resistant Gram-negative bacterial infections necessitates the
development of new treatments or the repurposing of available antibiotics. Here, treatment options
for treatment of these infections, recent guidelines and evidence are reviewed. Studies that included
treatment options for infections caused by multidrug-resistant Gram-negative bacteria (Enterobacterales
and nonfermenters), as well as extended-spectrum β-lactamase-producing and carbapenem-resistant
bacteria, were considered. Potential agents for the treatment of these infections, considering type of
microorganism, mechanism of resistant, source and severity of infection as well as pharmacotherapy
considerations, are summarized.