Gene Expression Analysis in an Animal Model of Cortical Dysplasia-IRRADIATED GROUP

Cortical Dysplasia (CD) is the histopathological substrate in almost half of all drug-resistant epilepsy. Little is known about the gene expression profile of CD. As such information may help target therapeutics more effectively, our aim was to perform a gene expression analysis of an animal model of cortical dysplasia induced by in utero irradiation. THIS SERIES (GSE13697) INCLUDES ALL (AND ONLY) EXPERIMENTAL SAMPLES--I.E. IRRADIATED/CORTICAL DYSPLASIA (9).皮质发育畸形（Cortical Dysplasia, CD）是近半数耐药性癫痫患者的病理组织学基础。目前针对CD的基因表达谱特征仍所知甚少。鉴于此类信息可为靶向治疗提供更有效的指导，本研究旨在对宫内照射诱导的皮质发育畸形动物模型开展基因表达分析。本数据集（GSE13697）包含全部且仅包含实验样本，即经照射处理的皮质发育畸形样本（共9例）。