Engineering of Corynebacterium glutamicum for growth and succinate production from levoglucosan as a pyrolytic sugar substrate

We deveolped the C. glutamicum strains that is able to utilize levoglucoan as sole carbon and produce succinate. To understand the cellular metabolism in a levoglucosan-utilizing strain, we compared the mRNA profiling of a levoglucosan-utilizing strains grown in either glucose or levoglucosan. Comparision of the transcriptome from a levoglucosan-utilizing strain & succinate-producing strain (BL-1-LGK) grown in either glucose (as a control) or levoglucosan (as an experiment) at 5 h