Conserved amino acid residues in four open reading frames of Indian HBV/D4 (IndD4) isolates compared with the previously reported residues at the same position in different subgenotypes of D (D1–D9).

Unique residues of IndD4 are underlined. The major amino acids are indicated in bold. aThe conserved domains of the open reading frame of HBV polymerase are indicated as follows: tp, terminal protein domain; sp, spacer region; rt, reverse transcriptase domain; rh, RNase H region. *, ** the overlapping surface and polymerase mutationsConserved amino acid residues in four open reading frames of Indian HBV/D4 (IndD4) isolates compared with the previously reported residues at the same position in different subgenotypes of D (D1–D9).