RNA-seq data for the effect of MSC-derived extract on periodontal ligament cells

This study aimed to investigate comprehensive gene expression changes in periodontal ligament cells after the treatment of the cells with cell extract from mesenchymal stem cells (MSC-ectract) using RNA-seq analysis. RNA-seq data was collected from periodontal ligament cells in control (non-treated for 24 hours) and experimental (treated with MSC-extract for 24 hours) group and compared. We have observed that MSC-extract enhanced the migration and proliferation of periodontal ligament cells and this RNA-seq results may explain the mechanism of the effect of MSC-extract on the cells. Because periodontal ligament cells have important role in wound healing process of periodontal tissues, MSC-extract may be useful for the regeneration of these tissues.