Association between TLR4 SNPs and LOAD risk by hypertension status.

All models were adjusted for age, gender, education, and ApoE e4 status.Abbreviations: LOAD, late-onset Alzheimer's disease; AOR, adjusted odds ratio; CI, confidence interval; SNP, single nucleotide polymorphism.Numbers in bold indicates statistically significant findings(pa0 copies, wild type; 1 copy, heterozygotes; 2 copies, homozygous variants.*The result remained significant (2 copies of variant SNP3 in hypertensive persons, p = 0.002) after controlling for type I error by using Bonferroni correction (α = 0.05/5).Before stratification, hypertensive patients showed a decreased the risk of LOAD (AOR = 0.41, 95% CI = 0.28–0.61).