Dexamethasone treatment of immortalized and primary cancer associated fibroblasts (CAF)

Glucocorticoids (GCs) are applied as concomitant medication in the course of ADT and chemotherapeutic treatment. therefore, it is essential to investigate specific effects on elevated stromal GR signaling and subsequently clarify a possible influence on tumor growth and disease progression. Overall design: Differential gene expression analysis of RNA-seq data from immortalized PF179T CAF and primary isolated CAFs upon dex and abi treatment. *** Raw data files are not available for the primary patient samples due to privacy concerns. ***