Number (%) of African Americans, Males, and Methylated Subjects by PAH Exposure Categories ( = 2.41)a.

Note: *Odds Ratios, 95% Confidence Intervals (OR, 95%CI) measuring the odds of high PAH exposure in African Amercians (Compared to Dominicans), males (Compared to Females), and subjects with methylated ACSL3 5′CGI (compared to those with unmehtylated CGI) assayed by MSPCR (N = 56).aThe PAH cutpoint value 2.41 was obtained from an ROC curve where we considered that methylation status could be determined by PAH exposure level. We considered ACSL3 5′CGI to be methylated (determined by MSPCR) above 2.41 and unmethylated below 2.41. The value of the cutpoint determined the sensitivity (i.e. number of correctly classified unmethylated subjects or true positives), the specificity (i.e. number of correctly classified unmethylated subjects or true negatives), and the number of false positives and false negatives. The median of samples with PAH exposure = 2.41 was 1.55.bp2.41 (compared to