Incidence of SARS-CoV-2 infection among healthcare workers before and after COVID-19 vaccination in a tertiary paediatric hospital in Warsaw

Conceptual proposition: to identify factors associated with HCW SARS-CoV-2 infection which make it possible to direct the management of health care services.
Research objective: to analyse the incidence of new SARS-CoV-2 infection among HCWs (before and after vaccination with BNT162b2) and to explore demographic and occupational factors associated with SARS-CoV-2 infection. To analyse the vaccine effectiveness against any SARS-CoV-2 infection in HCWs.

Collected data: age, gender, profession, workplace, vaccination status, voluntary SARS-CoV-2 nucleocapsid antibody test results (performed before implementation of the HCW vaccination programme in January 2021), SARS-CoV-2 RNA results from longitudinal universal screening (between October 20, 2020, and May 6, 2021, which correspond to epidemiological (epi) week 43, 2020 and epi week 18, 2021, a period covering the second and third epidemic waves in Poland), and SARS-CoV-2 RNA results from contact tracing, symptomatic testing, or testing upon return to work after sick leave (due to respiratory illness) collected from October 20, 2020, up to August 31, 2021 (epi week 43, 2020 to epi week 35, 2021).

概念性命题：识别与卫生保健工作者（HCW）SARS-CoV-2感染相关的因素，以指导医疗服务的管理方向。
研究目标：分析卫生保健工作者中SARS-CoV-2新感染的发生率（在接种BNT162b2疫苗前后）以及探讨与SARS-CoV-2感染相关的流行病学和职业因素。分析疫苗对任何SARS-CoV-2感染在卫生保健工作者中的有效性。
收集数据：年龄、性别、职业、工作场所、疫苗接种状态、自愿进行的SARS-CoV-2核壳抗体检测结果（在2021年1月实施HCW疫苗接种计划之前进行），以及从纵向普遍筛查中获得的SARS-CoV-2 RNA检测结果（2020年10月20日至2021年5月6日，对应于2020年第43个流行病学周和2021年第18个流行病学周，涵盖了波兰的第二和第三波疫情），以及从接触者追踪、症状性检测或在病假后返回工作岗位（由于呼吸系统疾病）收集的SARS-CoV-2 RNA检测结果（自2020年10月20日起至2021年8月31日，即从2020年第43个流行病学周到2021年第35个流行病学周）。