Gastric cancer grows under a hypoxic environment. HIF-1α is known to play an important role in controlling the production of reactive oxygen species (ROS) in the mitochondria under hypoxic conditions.
Statistically significant increase or decrease is highlighted +P <0.05, ++P <0.01, +++P <0.001 and - P <0.05, - - P <0.01, - - - P <0.001 respectively. nd = no data available, na = not applicable, ns
Ionizing radiation promotes cytosolic DNA sensing and consequent antitumor immune responses. But how tumor cell-intrinsic cytosolic DNA sensing is initiated by radiation remains poorly defined. Here,