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Supporting data and code for "Integrative network pharmacology, transcriptomic meta-analysis, and molecular docking suggest potential targets of Erzhi Wan in primary ovarian insufficiency"

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Zenodo2026-08-11 更新2026-08-13 收录
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This record contains processed network-pharmacology data, public-GEO transcriptomic analysis outputs, molecular-docking outputs, plot-source data, final figures, and analysis scripts supporting a purely computational study of Erzhi Wan in primary ovarian insufficiency. Public cohorts GSE296744 and GSE201276 were analyzed. The current docking analysis uses five prioritized compounds and eight core targets (ESR1, CYP19A1, AR, PGR, NR3C1, ESR2, CYP17A1, and BRAF). No wet-laboratory experiment was performed. Molecular docking is a computer simulation and not experimental validation. Keywords:Erzhi Wan; primary ovarian insufficiency; network pharmacology; transcriptomics; GEO; molecular docking; bioinformatics; reproducibility

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2026-08-11
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