Microarray analysis of gene expression after suppression of PBRM1 or KDM5C in 786-O VHL+/+ or VHL-/- cells

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108229

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1. PBRM1 loss elicited very similar transcriptional changes as KDM5C loss; 2. PBRM1 loss, and to a lesser extent KDM5C loss, elicited greater transcriptional response in VHL-/- cells than that in VHL+/+ cells. PBRM1 or KDM5C were suppressed by shRNA in 786-O cells VHL+/+ or VHL-/- before gene expression in triplicates was compared.

创建时间：

2018-11-30