首页/数据集/Musashi 2 regulates normal hematopoiesis and accelerates leukemogenesis (Leukemia cell lines)

Musashi 2 regulates normal hematopoiesis and accelerates leukemogenesis (Leukemia cell lines)

ChEBI2010-07-21 更新2026-07-21 收录

白血病发病机制

造血干细胞调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-22775 数据链接链接失效反馈

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资源简介：

Musashi 2 regulates normal hematopoiesis and accelerates leukemogenesis (Leukemia cell lines)

应用场景：

创建时间：

2010-07-21

DNA甲基化分析

白血病发病机制

DNA Methyltransferase 3A (DNMT3A) is frequently mutated in various hematopoietic malignancies; however, the underlying oncogenic mechanisms remain elusive. Here, we report that DNMT3A mutational ‘hots

NIAID Data Ecosystem130

Musashi 2 is a regulator of the hematopoietic stem cell compartment identified by a retroviral insertion screen and knockout mice

造血干细胞调控

基因功能研究

Musashi 2 is a regulator of the hematopoietic stem cell compartment identified by a retroviral insertion screen and knockout mice

ChEBI2011-05-21 更新20

Harnessing of the Nucleosome Remodeling Deacetylase complex controls lymphocyte development and prevents leukemogenesis

淋巴细胞发育调控

白血病发病机制

Harnessing of the Nucleosome Remodeling Deacetylase complex controls lymphocyte development and prevents leukemogenesis

ChEBI2011-11-13 更新00

Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]

白血病发病机制

CRISPRi筛选

Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

NIAID Data Ecosystem30

Supplementary Data S1 from Missense Mutations in Myc Box I Influence Nucleocytoplasmic Transport to Promote Leukemogenesis

白血病发病机制

MYC突变

AML-associated MYC mutations Cosmic

NIAID Data Ecosystem20