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Deep mutational scanning of mutant RBD libraries from SARS-CoV-2 variants and sarbevoviruses to detect mutations that reduce binding of polyclonal serum as well as mAbs.

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NIAID Data Ecosystem2026-05-10 收录
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We performed deep mutational scanning of the spike receptor-binding domain (RBD) from SARS-CoV-2 variant and saerecovirus viral lineages using yeast display to measure the effects of all amino-acid mutations on various on binding of antibodies or polyclonal plasma/sera.

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2025-10-30
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