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Single cell analysis of gene expression in the substantia nigra pars compacta of a pesticide-induced mouse model of Parkinson’s disease

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NIAID Data Ecosystem2026-03-13 收录
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https://figshare.com/articles/dataset/Single_cell_analysis_of_gene_expression_in_the_substantia_nigra_pars_compacta_of_a_pesticide-induced_mouse_model_of_Parkinson_s_disease/19197056
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"Single cell analysis of gene expression in the substantia nigra pars compacta of a pesticide-induced mouse model of Parkinson’s disease" Arshad H. Khan1, Lydia K. Lee2, Desmond J. Smith1,3 1 Department of Molecular and Medical PharmacologyDavid Geffen School of Medicine, UCLALos Angeles, CA 90095-1735 2 Department of Obstetrics and GynecologyDavid Geffen School of Medicine, UCLALos Angeles, CA 90095-6928 3 To whom correspondence should be addressed:Department of Molecular and Medical PharmacologyDavid Geffen School of Medicine, UCLABox 951735, 23-151A CHSLos Angeles, CA 90095-1735Email: DSmith@mednet.ucla.edu "Words" folder contains pdfs of the Manuscript and Supplementary Data. "Supplementary_Tables" folder contains results from single cell RNA-seq (scRNA-seq) analysis. "Behavior" folder contains data from pole and dot removal tests. "Single_cell_RNA_data" folder contains scRNA-seq data from substantia nigra pars compacta (SNpc) of mice treated with combined dosing of the pesticides maneb and paraquat (MNPQ) or saline. Raw and filtered output from 10X Genomics Cell Ranger pipeline provided.
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2022-02-18
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