Profiling Genome-wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells
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https://www.ncbi.nlm.nih.gov/sra/SRP017470
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资源简介:
We have engineered the chromatin-modifying apparatus and formulated a novel technology, termed Clickable Chromatin Enrichment with parallel DNA sequencing (CliEn-seq), to probe genome-wide chromatin modification within living cells. Overall design: Examine (E)-hex-2-en-5-ynylation mediated by engineered G9a Y1154A and GLP1 Y1211A in HEK293T cells.
创建时间:
2017-09-17



