Viable and apoptotic PMN populations in bulla fluids of Jbo/+ and Jf/+ mice are hypoxic.

Populations are expressed as percentages of their parent viable or apoptotic populations. The population of hypoxic apoptotic PMN was larger (aP = 0.0024) in 12–17 wk Jbo/+ than in 5–8 wk Jbo/+ mice and conversely, the normoxic apoptotic PMN population was larger (bP = 0.00027) in 5–8 wk Jbo/+ than 12–17 wk Jbo/+ mice. Propidium iodide staining showed that 7±2% of the Jbo/+ and 8±2% of the Jf/+ PMN populations were necrotic. Mean polymorphonuclear cell (PMN) percentages ± SEM. Statistics were performed using 2-tailed Student t-tests.