Study variables assessed at high altitude in baseline condition, after 15 minutes of slow breathing exercise and after 5 and 30 minutes of recovery.

Data are separately shown for Study A and B.*-pSpO2, blood oxygen saturation; ptO2– transcutaneous oxygen partial pressure; ptCO2– transcutaneous CO2 partial pressure; EtCO2– end tidal CO2 pressure in the exhaled air; SBP – systolic blood pressure; DBP – diastolic blood pressure; PP – pulse pressure; HR – heart rate; sPAP – systolic pulmonary artery pressure; RF – respiratory frequency; Vt – tidal volume; VE – minute ventilation; VA – alveolar volume; DlCO - pulmonary CO diffusion; TFC – thoracic fluid content.