A role for the nucleoporin Nup170p in chromatin structure and gene silencing [Agilent microarrays]

Embedded in the nuclear envelope, nuclear pore complexes (NPCs) not only regulate nuclear transport, but also interface with both transcriptionally active euchromatin and largely silenced heterochromatin, as well as the boundaries between these regions嵌于核被膜的核孔复合物（nuclear pore complexes, NPCs）不仅调控核运输，还可与转录活跃的常染色质、整体沉默的异染色质，以及这两类染色质区域间的边界发生相互作用。