HEK293T ishXrn1 cells were treated with doxycycline for 3-4 days to induce knock down of Xrn1, then transfected with a luciferase reporter with or without a 99bp sequence from the STOML2 gene inserted
Protein dynamics have a great influence on the binding pockets of some therapeutic targets. Flexible protein binding sites can result in transient binding pocket formation which might have a negative
Barcode indicates the screening plate sequence number defined by EPFL and Well Position gives the well. Plaque2.0-based infection scores are numberOfNuclei reporting the number of nuclei based on Hoec
This repository contains the bulk and single-cell RNA-Sequencing data for the manuscript "IAP dependency of T-cell prolymphocytic leukemia identified by high-throughput drug screening" by Pohly et al.
