Analysis of dephosphorylated HTT samples by cryoEM analysis 2019/05/01
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https://zenodo.org/record/3234166
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资源简介：
Project: High resolution structural analysis of purified HTT samples
Experiment: Analysis of dephosphorylated HTT samples by cryoEM analysis
Date completed: 2019/05/01
Rationale: We now have a good understanding of the global structure of HTT when in complex with HAP40 and our MALS and SAXS data suggest that apo HTT is likely self-associating and heterogenous in nature, despite high levels of purity. Dephosphorylating HTT from Sf9 cell production could alter its global structure sufficiently to allow high resolution structure determination by cryoEM.
创建时间：
2024-07-22
