Quality of Life – Family Impact Module in International Cohort Study of Children Born to Women Infected with Zika Virus During Pregnancy

Quality of Life – Family Impact Module, raw dataset. Scores entered for the Peds-QLTM 2.0 Family Impact
Module.
Study Description
This study was an extension of the International Prospective Observational Cohort Study of Zika in Infants and Pregnancy (ZIP Study). It was a prospective longitudinal cohort study that enrolled participants from the ZIP Study and other-approved studies and followed them for up to 3.5 years of age. Participants included children with confirmed or presumptive in-utero exposure to Zika virus and children matched by site, birth sex, and age (based on age at enrollment +/- 6 weeks) without confirmed or presumptive in-utero exposed to Zika virus. The primary aims were to determine the long-term neurodevelopmental outcomes among children born to women with documented ZIKV infection during their pregnancy and compare the long-term effects (e.g. on growth, vision, hearing and neurodevelopment) of confirmed in utero ZIKV-exposure compared to ZIKV-unexposed children. A total of 5 evaluations occurred about every 6 months over about a 2-year period beginning at approximately 18 months of age through 42 months of age. Children with confirmed or presumptive in-utero exposure to Zika virus and children matched by site, birth sex, and age (based on age at enrollment +/- 6 weeks) without confirmed or presumptive in-utero exposed to Zika virus.