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Crystal structure of yeast 20S proteasome in complex with the natural product carmaphycin A

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of yeast 20S proteasome in complex with the natural product carmaphycin A Descriptor: N-[(2S)-1-({(2S)-1-{[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]amino}-4-[(R)-methylsulfinyl]-1-oxobutan-2-yl}amino)-3-methyl-1-oxobutan-2-yl]hexanamide, Proteasome component C1, Proteasome component C11, ... Authors: Trivella, D.B.B, Stein, M, Groll, M. Deposit date: 2012-10-27 Release date: 2014-01-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. Chem.Biol., 21, 2014
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2012-10-27
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