Supplementary text from a clinical trial protocol for a planned pooled data analysis to define the optimal dosing regimen of dihydroartemisinin-piperaquine for perennial malaria chemoprevention during routine health facility visits - A pharmacokinetic randomised interventional study to optimise dihydroartemisinin-piperaquine dosing for malaria preventive treatment in Malawian infants: the OPTIMAL study

This is supplementary material detailing an analysis plan for a pooled population PK/PD analysis planned as part of an on-going OPTIMAL clinical trial aimed at generating data to inform antimalarial dosing regimen optimisation in infants