TDP-43 aggregation in NSC34 cells.

Values were averages of 4 or more experiments. Distribution of soluble TDP-43 fusion proteins was determined in cells that did not contain aggregates. All distribution was determined based on GFP signal except construct 1, which was determined by staining for TDP-43 (see Fig. 3 and the text). Nuc means nucleus; Cyto means cytoplasm; % transfected means the percentage of the transfected cells detected by visualizing GFP; % nucleus means percentage of aggregate-positive cells where the aggregates were located in the nucleus; % cytoplasm means percent of aggregate-positive cells where the aggregates were located in the cytoplasm; SE, standard error.