Mean (SD) CBF (mL/100 g/min) of NAWM and lesions in each grade.

P* refers to CBF within lesions compared that in NAWM in the same group.1Compared with grades 0 and I, CBF of NAWM in grades II and III, P value 2compared with grade II, CBF of NAWM in grade III, P value 3Compared with grade I, CBF within lesions in groups II and III, P value 4compared with grade II, CBF within lesions in group III, P value NAWM means normal-appearing white matter. RLV means right lateral of ventricle, LLV means left lateral of ventricle; RAV means right anterior of ventricle, LAV means left anterior of ventricle; RPV means right posterior of ventricle, LPV means left posterior of ventricle; WPV means whole periventricular areas; RCS means right centrum semiovale, LCS means left centrum semiovale.Mean (SD) CBF (mL/100 g/min) of NAWM and lesions in each grade.