JAK3 kinase domain in complex with 1-[(3S)-1-isobutylsulfonyl-3-piperidyl]-3-(5H-pyrrolo[2,3-b]pyrazin-2-yl)urea
收藏Protein Data Bank Japan2023-11-08 更新2026-03-21 收录
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JAK3 kinase domain in complex with 1-[(3S)-1-isobutylsulfonyl-3-piperidyl]-3-(5H-pyrrolo[2,3-b]pyrazin-2-yl)urea Descriptor: 1-{(3S)-1-[(2-methylpropyl)sulfonyl]piperidin-3-yl}-3-(5H-pyrrolo[2,3-b]pyrazin-2-yl)urea, Tyrosine-protein kinase JAK3 Authors: Kuglstatter, A, Shao, A. Deposit date: 2014-07-07 Release date: 2015-05-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Scaffold hopping towards potent and selective JAK3 inhibitors: discovery of novel C-5 substituted pyrrolopyrazines Bioorg.Med.Chem.Lett., 24, 2014
创建时间：
2014-07-07
