TF binding clusters in promoter correlate well with gene expression. We used ChIP-seq to map binding sites of the majority of highly expressed TFs in the cell. The size of clusters of TFs in the promo
ATAC-seq data from sorted control and ATRX-null microglia nuclei was analyzed to identify the top represented transcription factors binding sites displaying differential binding scores (top 2%) using
Meiotic recombination is initiated by developmentally programmed DNA double-strand breaks (DSBs). In S. cerevisiae, the vast majority of DSBs occur in the nucleosome-depleted regions at gene promoters