Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK055
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Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK055 Descriptor: (2S)-{[(3-{[(2-chloro-6-methylphenyl)carbamoyl]amino}naphthalen-2-yl)carbonyl]amino}(phenyl)ethanoic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... Authors: Nolte, R.T. Deposit date: 2008-06-06 Release date: 2009-01-27 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy. Bioorg.Med.Chem.Lett., 19, 2009
创建时间:
2008-06-06



