Human CYP3A4 bound to an inhibitor
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Human CYP3A4 bound to an inhibitor Descriptor: Cytochrome P450 3A4, Nalpha-{(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl}-N-[(pyridin-3-yl)methyl]-D-phenylalaninamide, PROTOPORPHYRIN IX CONTAINING FE Authors: Sevrioukova, I.F. Deposit date: 2018-05-01 Release date: 2019-04-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.802 Å) Cite: Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
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2018-05-01
