Study of Dosage of Prophylactic Intravenous Ephedrine for Spinal Induced Hypotension During Spinal Anesthesia in Cesarean Section in Telangana Population

Background: Spinal anaesthesia-induced hypotension occurs frequently, particularly in adults and patients undergoing cesarean section. Spinal anaesthesia-induced hypotension (SAIH) is caused by arterial and venous vasodilatation resulting from the sympathetic blockade. Ephedrine has traditionally been considered the vasoconstrictor of choice. Method: Out of 70 (seventy), 35 were administered ephedrine and 35 in the controlled group were administered the same quantity of normal saline during spinal anaesthesia. Hemodynamic and neonatal outcomes were noted and compared. Results: In the comparison of systolic BP between both the groups at the time intervals of 1, 2, 3 and 15 there were significant values (p<0.001). Apgar 1 minute, 5 minutes, and umbilical cord PH were compared with controls and were also highly significant (p<0.001). Conclusion: The present pragmatic study has confirmed that I.V. infusion of Ephedrine was more effective than crystalloid preloading in preventing hypotension in parturients undergoing cesarean section without causing hemodynamic complications.