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Transcriptome data of B cells in patients with primary Sjögren's syndrome

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE135809
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We compared subsets of B cells as follows: Bm1 cells; CD38-IgD+, naïve B cells; CD38+IgD+, pre-germinal centre B cells; CD38highIgD+ and memory B cells; CD38±IgD that were collected from patients with primary Sjögren's syndrome. As a result, list of 623 differentially expressed genes was created. We found interferon signature genes and HLA genes were mostly up-regulated in patients compared to healthy controls. Examination between patients with primary Sjögren's syndrome and healthy controls
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2020-06-29
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