Effect of individual parameter on key hemodynamic variables during supine and HUT.

: mean arterial pressure; : heart rate; : stroke volume; : mean cardiac output; : mean left atrial pressure; : mean pulmonary arterial pressure; : mean central venous pressure; : LV end diastolic volume; : RV end diastolic volume; Columns from fourth to ninth refer to the simulation repeated (using healthy parameters) by individually modifying the following quantities to that used for the heart failure scenario: : LV contractility; : RV contractility; : baseline systemic vascular resistance; : pulmonary vascular resistance; : total blood volume; : LV end diastolic stiffness; : desensitized effector response.