S100A8/A9-related myocardial injury after non-cardiac surgery: RNA sequencing analysis in a novel mouse model

The aim of this study was to develop a new mouse model of myocardial injury after non-cardiac surgery (MINS) and to elucidate its pathophysiology. Male C57BL/6 mice underwent abdominal surgery under sevoflurane anesthesia, and myocardial samples were collected at multiple time points post-surgery. Gene expression profiling using RNA sequencing data from these samples was performed to investigate the molecular changes associated with MINS. RNA-seq profiling of mouse heart tissue from male C57BL/6 mice collected at multiple time points post-abdominal surgery under sevoflurane anesthesia