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miR-146a promotes the initiation and progression of melanoma by activating Notch signaling

ChEBI2014-02-18 更新2026-07-21 收录

黑色素瘤分子机制

Notch信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-39983 数据链接链接失效反馈

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资源简介：

miR-146a promotes the initiation and progression of melanoma by activating Notch signaling

应用场景：

创建时间：

2014-02-18

Notch信号通路

组蛋白修饰与转录调控

The study deals with the elucidation of potential interaction partners of the intracellular domain of the transmembrane receptor Notch1, termed NICD. The NICD is released from the cytoplasmic tail of

NIAID Data Ecosystem110

Importance of RAD6B in activation of canonical WNT signaling in melanoma development

黑色素瘤分子机制

Wnt信号通路调控

We have demonstrated that RAD6B, a ubiquitin conjugating enzyme that is a principal component of translesion synthesis pathway, stabilizes and transcriptionally activates beta-catenin by lysine 63-lin

NIAID Data Ecosystem60

Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [Rec1_ChIP-seq]

癌症三维基因组学

Notch信号通路

Purpose: To investigate the impact of oncogenic Notch on the 3D genome organization of cancer cells. Methods: We generated cohesin HiChIP and 1D epigenomic data sets in two different Notch-dependent c

NIAID Data Ecosystem50

Significant GO terms for the top 300 genes that distinguish primary from cutaneous melanoma.

黑色素瘤分子机制

基因功能注释

Significant GO terms for the top 300 genes that distinguish primary from cutaneous melanoma.

NIAID Data Ecosystem70

m6A IP sequencing analysis of m6A mRNA methylation regulation by FTO in melanoma cells. m6A IP sequencing analysis of m6A mRNA methylation regulation by FTO in melanoma cells

RNA表观遗传学

黑色素瘤分子机制

N6-methyladenosine (m6A) RNA methylation is the most abundant internal chemical modifications in eukaryotic messenger RNA (mRNA) as well as long non-coding RNA (lncRNA). Recently, m6A RNA methylation

NIAID Data Ecosystem50

miR-146a promotes the initiation and progression of melanoma by activating Notch signaling

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