Nerve Growth Factor in Complex with Fab from humanized version of mouse mAb 911 (tanezumab)
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Nerve Growth Factor in Complex with Fab from humanized version of mouse mAb 911 (tanezumab) Descriptor: Beta-nerve growth factor, GLYCEROL, tanezumab Fab heavy chain, ... Authors: Eigenbrot, C, Ultsch, M. Deposit date: 2012-03-27 Release date: 2014-04-02 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes. MAbs, 6
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2012-03-27
