Highly Stereoselective Synthesis of 1,2,3-Trisubstituted Indanes via Oxidative <i>N</i>-Heterocyclic Carbene-Catalyzed Cascades
收藏NIAID Data Ecosystem2026-03-07 收录
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Three stereocenters are formed in the carbene catalyzed cascade reaction of enals with various β-diketones to give the corresponding indane derivatives with excellent stereoselectivities. The products are readily transformed to the corresponding 1,2,3-trisubstituted indane derivatives, which represent privileged substructures in medicinal chemistry.
创建时间：
2017-05-05
