AMPK signaling pathway, a fuel sensor and regulator, promotes ATP-producing and inhibits ATP-consuming pathways in various tissues. AMPK is a heterotrimer composed of alpha-catalytic and beta and gamm
Western Blot data deposit for the manuscript "Targeted degradation of the α-ketoglutarate dehydrogenase mediated by a mitochondrial DNAJC protein regulates metabolism"
The thyroid hormone triiodothyronine (T 3 ) activates thermogenesis by uncoupling electron transport from ATP synthesis in brown adipose tissue (BAT) mitochondria. Although T 3 can
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cho
HCAR3 (GPR109B) is activated by 3-hydroxyoctanoic acid (3HO) (Ahmed et al. 2009) and nicotinic acid (niacin) (Wise et al. 2003). 3HO is an intermediate of fatty acid beta-oxidation. Under conditions o