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Crystal structure of the cAMP-dependent protein kinase A cocrystallized with aminofasudil and PKI (5-24)

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal structure of the cAMP-dependent protein kinase A cocrystallized with aminofasudil and PKI (5-24) Descriptor: 5-(1,4-diazepan-1-ylsulfonyl)isoquinolin-1-amine, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha Authors: Oebbeke, M, Gerber, H.-D, Heine, A, Klebe, G. Deposit date: 2020-02-17 Release date: 2021-03-31 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Fragment based drug design - Small chemical changes of fragments effecting big changes in binding To Be Published
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2020-02-17
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