PrPSc distribution in nasal cavity and olfactory bulb.

1Subepithelium of nasal mucosa; NALT, nasal-associated lymphoid tissue.2Olfactory bulb structures include the ONL, outer nerve layer; GL, glomerular layer; OPL, outer plexiform layer, M, mitral layer; IPL, inner plexiform layer.3The relative intensity of PrPSc deposition in the hamster brain infected with CWD was scored on a 0 to 3 scale with 0 = no immunoreactivity, 1 = mild immunoreactivity, 2 = moderate immunoreactivity, and 3 = intense immunoreactivity. For each hamster a minimum of twenty-four tissue sections were examined spanning the middle to posterior portion of the nasal cavity.nd, not done.