The protein-protein interactions of SMAD4-D351H, SMAD4-R361H, SMAD4-R361C, SMAD4-G386D or SMAD4 wild type detected using the NanoLuc luciferase-based bioluminescence resonance energy transfer (BRETn)
P311 is a highly conserved multifunctional protein. However, it does not belong to any established family of proteins, and its biological function has not been entirely determined. This study aims to
The top 10% of the proteins ranked by degree, closeness and eigenvector centrality scores were selected. The proteins that are present in common across three groups were defined as central. The centra
This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.
