miR-432 augments the activation of β-catenin pathway and decreases apoptosis after MI/R injury.
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miR-432 mixed transfection reagent was injected into the myocardium of mice to regulate miR-432 expression 48 hours prior to MI/R injury. 24 hours of MI/R injury, we harvested the mice heart and used western blot method to analyze the expression of β-catenin, p-GSK-3β and GSK-3β, Bax and Bcl2, and cleaved-caspase 3 protein expression, and used TUNEL staining to analyze the cardiomyocyte apoptosis. 8 mice each group, P value was calculated by post-hoc comparisons
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创建时间：
2022-05-19
