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GPR174 acts as a novel prognostic biomarker for patients with sepsis via regulating inflammatory response

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP341663
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资源简介:
RNA-seq showed that Gpr174 deficiency induced a marked phenotypic shift toward multiple immune response pathways in septic mice. Potential mediators of immune response, including dendritic cell-specific transmembrane protein and macrophage mannose receptor 1 were highly upregulated, while interleukin-12 subunit alpha and Sialoadhesin downregulated in Gpr174-KO mice after CLP challenge.
创建时间:
2021-10-18
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