官方服务:
资源简介:
RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
应用场景:
创建时间:
2019-04-05
相关数据集
Control vs. PGISp spine samples
OBJECTIVES: Ankylosing spondylitis (AS) is unique in its pathology where inflammation commences at the entheses before progressing to an osteoproliferative phenotype generating excessive bone formatio
NIAID Data Ecosystem90
HOXA5 counteracts stem cell traits by inhibiting Wnt signaling. Homo sapiens
Here we identify HOXA5 as an important repressor of intestinal stem cell fate in vivo and identify a reciprocal feedback between HOXA5 and Wnt signaling. HOXA5 is suppressed by the Wnt pathway to main
NIAID Data Ecosystem40
HMGA1 acts as an epigenetic gatekeeper of ASCL2 and Wnt signaling during colon tumorigenesis
Mutated cells undergo changes in chromatin accessibility and gene expression, resulting in aberrant proliferation and differentiation, although how this occurs is unclear. HMGA1 chromatin regulators
NIAID Data Ecosystem10
Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development
We use a 3D in vitro organoid model to study the early phase of colorectal cancer development. In reaction to Wnt activation we observe downregulation of location specific genes and differentiation ma
NIAID Data Ecosystem80
DataSheet1_NAP1L1 Functions as a Novel Prognostic Biomarker Associated With Macrophages and Promotes Tumor Progression by Influencing the Wnt/β-Catenin Pathway in Hepatocellular Carcinoma.ZIP
Hepatocellular carcinoma (HCC) is regarded as one of the universal cancers in the world. Therefore, our study is based on clinical, molecular mechanism and immunological perspectives to analyze how NA
NIAID Data Ecosystem30



