Crystal structure of thrombin in complex with inhibitor 15
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Crystal structure of thrombin in complex with inhibitor 15 Descriptor: 2-{3-[(benzylsulfonyl)amino]-6-methyl-2-oxopyridin-1(2H)-yl}-N-({1-[2-(tert-butylamino)-2-oxoethyl]-4-methyl-1H-imidazol-5-yl}methyl)acetamide, Hirugen, Prothrombin Authors: Yan, Y. Deposit date: 2008-01-23 Release date: 2008-03-18 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Structure-based design of novel groups for use in the P1 position of thrombin inhibitor scaffolds. Part 2: N-acetamidoimidazoles. Bioorg.Med.Chem.Lett., 18, 2008
创建时间:
2008-01-23



