Quantitative analysis of gene expressiona at 24 hpf.

a: a relative gene expression level was determined and then normalized to the expression level of β-actin (actb1). The values (mean ± standard deviation) are the relative gene expression levels of morphants compared to those of the wild type (un-injected) of the same batch.* indicates significant difference (p** indicates significant difference between adar2MOt-p53AUG and adar2MOt.b: Accession numbers are listed in Table S1. neuroD and neurog1 (neurogenin 1) are proneuron genes; ccng1(cyclin G1), mdm2 and Δ113p53 (a short isoform of p53 transcribed from an internal promoter) are p53-responsible genes. 3′-p53 and 5′-p53 respectively represent transcripts encoding all the isoforms of p53 and long isoform of p53. sox9a and sox9b are expressed in the neural crest cells and other cell types.c: n, number of independent injection