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Deletion and overexpression of the scaffolding protein IQGAP1 promotes HCC

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP258972
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资源简介:
IQGAP1 is a scaffolding protein that is upregulated in liver cancer. We tested its role in promoting tumor growth using a mouse model of hepatocellular carcinoma initiated by diethylnitrosamine (DEN) injection. IQGAP1-knockout mice, heterozygous mice, and wild-type mice were followed for 50 weeks after DEN injection and tumor burden was assessed.
创建时间:
2021-02-09
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