Cocrystal structure of Drosophila melanogaster TDO with a bound compound
收藏Protein Data Bank Japan2025-10-22 更新2026-04-19 收录
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Cocrystal structure of Drosophila melanogaster TDO with a bound compound Descriptor: (~{R})-(7-chloranylimidazo[1,5-a]pyridin-5-yl)-(1-phenyl-1,2,3-triazol-4-yl)methanol, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan 2,3-dioxygenase Authors: Wicki, M, Mac Sweeney, A. Deposit date: 2024-06-12 Release date: 2025-04-23 Last modified: 2025-10-22 Method: X-RAY DIFFRACTION (2.121 Å) Cite: Cellular Potency Optimization of Novel Heme-Binding Imidazo[5,1- b ]thiazoles, Imidazo[1,5- a ]pyridines and Pyrazines as Potent IDO1 Inhibitors Devoid of Cytochrome P450 Inhibition. J.Med.Chem., 68, 2025
创建时间：
2024-06-12
