Expression of 97 surface markers and 462 mRNAs in 70017 cells from healthy young, healthy old and leukemic human bone marrow

Name: Expression of 97 surface markers and 462 mRNAs in 70017 cells from healthy young, healthy old and leukemic human bone marrow
Creator: Triana, Sergio; Velten, Lars; Haas, Simon; Paulsen, Malte; Vonficht, Dominik; Jopp-Saile, Lea
Published: 2021-06-15 00:00:00
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Figshare2021-06-15 更新2026-04-08 收录

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https://figshare.com/articles/dataset/Expression_of_97_surface_markers_and_462_mRNAs_in_70017_cells_from_healthy_young_healthy_old_and_leukemic_human_bone_marrow/13397651/1

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Seurat v3 object ASSAYS:AB: Antibody expression dataRNA: mRNA expression dataintegrated: Antibody and mRNA expression matrices were concatenated and data was integrated across patients using scanorama DIMENSIONALITY REDUCTIONMOFA: Multi-OMICS factor analysis to integrate AB and RNA data. MOFA was run on scanorama-integrated data and served as input for clustering and further dimensionality reduction.MOFAUMAP: UMAP performed on MOFA dimensions. Display used in the manuscript. MOFATSNE: UMAP performed on MOFA dimensions. METADATABatch: Source individual (BM1-3, Aged1-3, AML1, AML3 and Q59. Q59 is called AML2 in the manuscript).class: Type of individual (healthy young, healthy old or AML).

提供机构：

Triana, Sergio; Velten, Lars; Haas, Simon; Paulsen, Malte; Vonficht, Dominik; Jopp-Saile, Lea

创建时间：

2021-03-15