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Genome-wide analysis of high glucose and DZNep (EZH2 inhibitor) induced gene expression by mouse podocytes

ChEBI2015-12-09 更新2026-07-12 收录

肾病分子机制

表观遗传调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-60038 数据链接链接失效反馈

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Genome-wide analysis of high glucose and DZNep (EZH2 inhibitor) induced gene expression by mouse podocytes

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创建时间：

2015-12-09

肾病分子机制

细胞自噬通路

It is well-established that mitophagy leads to Diabetic Nephropathy (DN) and renal failure. Mitophagy mediated by a Hypoxia-inducible factor-1α (HIF-1α) plays a beneficial role in many diseases. Never

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Data Sheet 7_Investigating the metabolic reprogramming mechanisms in diabetic nephropathy: a comprehensive analysis using bioinformatics and machine learning.csv

肾病分子机制

生物标志物发现

BackgroundDiabetic nephropathy (DN) is a common complication of diabetes, characterized by damage to renal tubules and glomeruli, leading to progressive renal dysfunction. The aim of our study is to e

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ZDHHC15 mediates Hippo/YAP pathway palmitoylation and regulates tumor progression [TOV-112D]. ZDHHC15 mediates Hippo/YAP pathway palmitoylation and regulates tumor progression [TOV-112D]

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YAP信号通路

The Post-translational modification of Hippo/YAP pathway members plays an important role in regulating the activation of Hippo/YAP pathway and its effects in tumors. S-Palmitoylation, also known as S-

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Multimodal learning of noncoding variant effects using genome sequence and chromatin structure

变异功能预测

表观遗传调控

ncVarPred-1D3D: pretrained models of Sei (PMID: 35817977) + our 3D structure embedding models are shared. The models are trained and validated using DeepSEA (PMID: 26301843) selected 200 bp regions (w

Zenodo2023-08-08 更新00

DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

表观遗传调控

甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

Genome-wide analysis of high glucose and DZNep (EZH2 inhibitor) induced gene expression by mouse podocytes

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